More US Parents Are Refusing Vitamin K for Newborns, Study Reports
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A routine medical practice that has protected American newborns for over six decades is now facing unexpected resistance. Hospitals across all 50 states are reporting a troubling pattern, one that has left pediatricians and neonatologists increasingly alarmed. For most parents, the first hours after birth involve a whirlwind of emotions, paperwork, and medical procedures. Among these procedures is a simple injection that takes mere seconds to administer. Most families accept it without question. But a growing number are saying no. A study published in the Journal of the American Medical Association in December 2025 has quantified what many doctors suspected but couldn’t prove. And the findings have sparked urgent conversations in medical communities nationwide. What would lead parents to refuse a decades-old preventive measure for their newborns? And what happens to babies who don’t receive it?What the Numbers Show
Researchers analyzed electronic medical records from more than 5 million newborns delivered in 403 hospitals between January 2017 and December 2024. Data came from Epic Systems’ Cosmos database, covering facilities across all 50 states and Washington, D.C. Results revealed that roughly 4% of babies born during this period did not receive vitamin K shots. In raw numbers, that translates to approximately 200,000 newborns. More concerning than the overall percentage is the trajectory. In 2017, refusal rates sat at 2.92%. By 2024, that figure had climbed to 5.18%. After adjusting for various factors, researchers found the rate rose from 2.57% to 4.62% over the same period. Dr. Kristan Scott, a neonatologist at Children’s Hospital of Philadelphia and the study’s lead author, said he and his colleagues had noticed more parents declining the shot in their own practices. That observation prompted the research. Still, the results caught him off guard. “The increase is not surprising, but the degree to which it did increase did catch me off guard,” Scott said.Why Newborns Need Vitamin K

What Happens When Babies Skip the Shot
Newborns who do not receive prophylactic vitamin K face serious risks. According to the Centers for Disease Control and Prevention, babies who skip the shot are 81 times more likely to develop severe bleeding than those who receive it. Bleeding episodes can occur anytime within the first six months of life. Early bleeding may appear within the first 24 hours. Classic vitamin K deficiency bleeding typically occurs between days two and seven. Late-onset bleeding, the most dangerous form, can strike between two weeks and six months after birth. Symptoms range widely in severity. Some infants experience bruising or excessive bleeding when the umbilical cord is cut. Others suffer gastrointestinal bleeding. But the most feared complication involves bleeding inside the brain, which functions essentially as a stroke in a newborn. Late-onset vitamin K deficiency bleeding carries a mortality rate between 20% and 50%, according to various studies. Survivors often face lasting neurological damage. Dr. Scott noted that at the Children’s Hospital of Philadelphia, staff have observed increases not only in vitamin K refusal but also in bleeding cases. He believes further research will confirm a correlation between rising refusal rates and more bleeding events nationwide.Which Families Are Refusing

Misinformation and Vaccine Skepticism Are Fueling the Trend

A Problem Hidden by Success
One of the greatest challenges doctors face when counseling hesitant parents is the very success of vitamin K prophylaxis. Six decades of routine administration have made vitamin K deficiency bleeding virtually invisible to the general public. Dr. Hand described this paradox in stark terms. “These treatments have been so effective that people don’t understand the consequences. They have never seen babies with severe bleeding, so they think it doesn’t exist,” Hand said. “But you don’t see it because we are treating these kids.” McKee-Garrett has heard reports of vitamin K deficiency bleeding cases in the Houston area, something that was extremely rare for decades after U.S. hospitals began widespread administration. She called it a preventable disease that should not be occurring at all. Parents today have no memory of an era when newborn bleeding was a common concern. Without that lived experience, the risk feels abstract. When weighed against fears stoked by online misinformation, some families conclude the shot is unnecessary. Doctors worry they are now creating a new population of vulnerable newborns. As refusal rates climb, more infants enter their first months of life without protection against a known and preventable danger.What Experts Are Calling For

A Preventable Crisis in the Making
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